Carboxymethylcellulose Calcium (CMC-Ca) Superdisintegrant | Muaj Peev Xwm O thiab Ua Rau Cov Tshuaj Yaj Sai Sai | Ua Raws Li USP/EP/ChP
Tshuaj Qib Carboxymethylcellulose Calcium (Carmellose Calcium, CMC-Ca)
Txheej Txheem Cej Luam Khoom
Carboxymethylcellulose Calcium yog cov ntsev calcium ntawm polycarboxymethyl ether ntawm celluloseNws yog ib qho tshuaj siv ntau yam tshuaj uas siv dav dav ua ib qho disintegrant, binder, thiab diluent hauv cov ntaub ntawv khoom noj khoom haus xws li cov ntsiav tshuaj thiab cov tshuaj ntsiav.Tsis zoo li nws cov sodium counterpart, cov calcium ntsev muaj qhov zoo ntawm cov sodium-free formulation, ua rau nws tshwj xeeb tshaj yog rau cov neeg mob plawv thiab cov neeg mob uas tsis muaj sodium..
Lub Npe Khoom:
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Lub Npe Tshuaj:Carboxymethylcellulose Calcium / Carmellose Calcium
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Tus lej rau npe CDE:F20230000328
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Cov lus txhais:Calcium carboxymethylcellulose, Calcium CMC, CMC-Ca, Carmellose Calcium
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Tsos:Dawb rau daj-dawb los yog dawb-dawb hmoov, hygroscopic tom qab ziab
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Kev yaj tau:Yuav luag tsis yaj hauv dej, acetone, cawv, thiab toluene; swells hauv dej los ua ib qho suspension
Cov Nta Tseem Ceeb & Cov Txiaj Ntsig
1. Kev Ua Kom Tawg Zoo Tshaj Plaws
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Insoluble hauv dej tab sis sai sai o tuajntau zaus nws lub ntim thawjthaum kov cov dej nruab nrab
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Tsim kom muaj lub zog ua kom cov ntsiav tshuaj tawg sai sai
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Ua kom sai thiab tiav disintegration rau kev yaj tshuaj zoo dua
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Ua tau zoo txawm tias nyob rau hauv cov ntsiav tshuaj tawv uas lwm cov khoom tawg yuav tsis ua haujlwm txaus
2. Cov Khoom Siv Ntau Yam
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Ua kom tawg:Kev ua haujlwm tseem ceeb ua cov ntsiav tshuaj disintegrant ntawm 0.5-15% concentration
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Cov Ntawv Txuas:Cov khoom siv zoo hauv cov txheej txheem granulation ntub
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Cov Tshuaj Tua Kab Mob/Cov Tshuaj Muab Tshuaj:Yuav ua haujlwm ua cov ntsiav tshuaj diluent
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Kev Pab Txhawb Kev Ncua:Siv ua tus stabilizer rau kev ncua hauv kev npaj tshuaj noj thiab tshuaj pleev
3. Qhov Zoo Tshaj Plaws Uas Tsis Muaj Sodium
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Tsis muaj sodium - zoo tagnrho rau cov tshuaj kho mob plawv thiab cov neeg mob uas tsis noj sodium ntau
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Teb cov kev xav tau ntawm cov neeg mob thiab cov cai tswjfwm uas nce ntxiv rau cov tshuaj sodium tsawg
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Ua tau raws li cov qauv kev tsim khoom huv thiab kev noj qab haus huv
4. Kev Sib Txuas Zoo API Zoo heev
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Tshwj xeeb tshaj yog zoo raucov tshuaj cephalosporin, nrog rau cov khoom ua kom yaj zoo dua qub
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Cov qauv chelating zoo pab tau qee cov chav kawm API
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Sib xws nrog ntau yam khoom xyaw nquag xws li: Pioglitazone HCl, Aminophylline, Berberine HCl, Milnacipran HCl, Cefixime, Nicorandil, thiab ntau lwm yam
5. Cov Khoom Siv Zoo Tshaj Plaws
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Kev sib zog zoo heev thiab lub zog ntawm ntsiav tshuaj
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Tswj cov ntsiav tshuaj kom ruaj khov thaum ua kom cov khoom tawg sai sai
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Cov khoom ntws zoo rau kev sib txhuam ncaj qha
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Ruaj khov txawm tias hygroscopicity - khaws cia rau hauv cov thawv kaw zoo
6. Cov Cai thiab Cov Qauv Zoo